BfN Schriften 239 - Immunogenicity of GM peas. Review of immune effects in mice fed on genetically modified peas and wider impacts for GM risk assessment
This report reviews a scientific study by Prescott et al. (2005) which identified a higher immunogenic potential for a bean-derived alpha amylase inhibitor expressed in GM peas compared to the native bean-derived protein using a mouse model.
This report investigates three main questions. First, are the conclusions in the Prescott paper fully supported by the presented experimental results? Second, is the animal model applied relevant for GM food risk assessment? Third, wouldthe GM pea have alerted risk assessors if undergoing the ‘standard’ risk assessment procedure?